Possible cure? not yet ... But years of remission: some 405 (and soon 1045) patients included in Short Cycle trials show that we can go from daily HAART (HIV) , gradually, to less and keep the virus undetectable with a single weekly dosing. Patented ICCARRE, now recommanded by French Guidelines, and HYPO-DOLU: Why? For whom? How? It's explained here...
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Saturday, August 29, 2015
BREATHER: Fiat Lux !
This paper was originally published here, in French. We provide the google translation for your convenience. Proper translation will come soon. Some practical aspects may differ where you live.
BREATHER: Fiat Lux !
Breather: Fiat Lux ...!
The truth awaits the dawn next to a candle. The window glass is neglected.
The tests, the results are convincing. They were already there. Others come ... Facts are stubborn ... The information is sparse. Each in a different newspaper, to years of differences, in English ... Whatever ... just gather the facts.
It's pretty exciting in itself. Better than a whodunit ... One draws the ball and through the frosted glass is observed.
Breather: Fiat Lux ...!
All major media covered that concern us CROI 2015, the USA. All were there ... Postponed Breather: aidsmap (UK), i-based (UK), vih.org (FR). etc., etc ? Really ?? No...
On the other major support (US, CA, DE ...): it's radio silence ... A silence that speaks.
The webcast is yet in the politically correct ... So there will be material to search ...
http://tinyurl.com/HPC-BREATHER-WC
Breather changes the game ... The cumulative number of patients in 5/7, published, was 20 + 50 + 50 (Photo Faucy, Iccarre-1).
Add Breather: ca 220 double! When we have ANRS 162-4D, there will be 320, and fifty more Garches: we approach the 400 ... As long as Canada and make a difference ...
400 is the target of a marketing authorization or FDA test ... Well enough for RTU ...
We give (sit ...) Efavirenz + AZT to young people, including kids 8 years!
Those who were lucky enough (sic) had Atripla ® instead ... we understand the motivation of doctors!
BREATHER HIV kids children child HIV AIDS MSF Efavirenz
4 million infected children, 2 million children waiting for treatment, 1 to 2 million under EFV + ZDV (XTC +), 250,000 newly infected each year!
So yes ... Breather is a major information
Yet young people, they do not care ... What they kiffent: the weekend of freedom with friends, thinking ... mmm ... something else ...
They were as much to remain undetectable ... Youth of Breather ... and me too for that matter!
Breather HIV viral load HIV viral load undetectable limit of detection Atripla ICCARRE
Good Night and Good wad young! You is foooooormidables !!!
Here ... indignant and rebellious! In ICCARRE 1/7 after my breakfast. Sunday, rose Four color is NADA all week! And Hypo-Dolu is kif: that happiness ...
The truth awaits the dawn next to a candle. The window glass is neglected.
Saturday, August 22, 2015
Good Job Kids! (BREATHER)
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This paper was originally published here, in French. We provide the google translation for your convenience. Proper translation will come soon. Some practical aspects may differ where you live.
Good Job Kids! (BREATHER)
Congratulations kids! (BREATHER)
In my country, tender evidence of spring and the badly dressed birds are preferred to distant goals.
The test Breather (penta 16) is here:
http://tinyurl.com/HPC-BREATHER1
The Webcast is super interesting:
http://tinyurl.com/HPC-BREATHER-WC
Transcription and translation here:
BREATHER 5/7 Clinical Trial
The bibliographic notes follow:
www.tinyurl.com/CHE-BREATHER
Here is a summary:
Breather HIV HIV Efavirenz Leibowitch ICCARRE
Test results BREATHER (Small pause) with the combo used, it is safe for HIV + youth to have a short break at the weekend.
BREATHER (Petite Pause) was set up to check if young people could have a break Weekend safely compared to efavirenz daily.
199 HIV + youth 8 to 24 years, all in the treatment of HIV, and undetectable, all on a combination containing efavirenz. By lot, half continued in 7/7, 5/7 in the other half.
After a year, young people in 5/7 were just as likely to have their virus under control than those in 7/7. Very few viral rebound (6 5/7 and 7 7/7 for the group). 6 5/7 in check were handed over 7/7, and again became undetectable. No excess risk of resistance was observed.
Some young people were asked about their views and experiences in 5/7. For starters, some of them go from 7/7 to 5/7 was confusing and disturbing. However, once they had adapted to weekends without meds, young people have enjoyed this freedom, and preferred to 7/7.
iccarre Breather HIV HIV Atripla Efavirenz Leibowitch Butler AIDS AIDS
Me, taken weekly, tomorrow, Sunday. Monday I take the plane ... without my meds! Phew ...
In my country, tender evidence of spring and the badly dressed birds are preferred to distant goals.
Sunday, August 16, 2015
The first step
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This paper was originally published here, in French. We provide the google translation for your convenience. Proper translation will come soon. Some practical aspects may differ where you live.
The first step
The first step
It is sometimes difficult to make the first move: jump Sunday socket ... Many do, incidentally ...
Discussion with another doctor:
What surprised me greatly is that he is afraid, as part of the therapeutic relief, non patient compliance. To know that many do not have the necessary rigor to a specific outlet and a non taken precise treatment. "Are you sure that if you do not take your tablet on Sunday and Friday and take Saturday and other days you will follow them? Do not go you invert days? In forget others? Do not think not the daily routine and taken at the same time is less risky? " me he asked.
Doctor LIOTIER Iccarre HIV cure HIV doctor first step Eviplera relief
So I reassured. I told him that I was determined relative to the relief. I just told him that my relief works "psychologically" I needed a yes from him, even riquiqui.
But this ... No need to count on it!
A compatible version with the planning of Safe Practice Guide 4-of-7 consists in 1/2 steps; can be 5.5 to 7 for example. 2 methods:
A- take half a tablet to the 0.5
B- the last day of 5, take, not one dose, but 2 doses, ideally several hours apart.
I used both method A as B.
They allowed me to 'pass' psychological caps. And initiate the first move.
However, I have never departed from my rule closer CV, nor of consecutive days (not sprinkling).
The weekly break, extended to Weekend, then the extended weekend has an advantage over other possible planning:
Whatever the generation, the kid at the senior, Weekend, it is easy to identify, we expect it, one feels, and knows only too well that an end ...
I've been there, I know that the fear is real ... But that too, it has a purpose ...
Saturday, August 1, 2015
A practical guide to 4/7
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This paper was originally published here, in French. We provide the google translation for your convenience. Proper translation will come soon. Some practical aspects may differ where you live.
A practical guide to 4/7 The Practical Guide 4/7
Just after the blood test, I take my meds (for the week at once).
Presto, after taking blood, on Monday morning, and presto! It's finish !
Iccarre HIV cure HIV AIDS testing protocol guide relief memento Jacques Leibowitch
We know explain how Tivicay ® (dolutegravir) is different (higher ...) to other molecules and therefore allows to reinvent treatment.
Where Leibowitch had believed succeed (Stalingrad test) definitively, it has, in fact, that the enemy content and, through trial and error, developed a method which is not bad at all .. .
But aside from that, it's dolutegravir the atomic bomb: nothing grows back.
Mark Wainberg (McGill, Montreal) published an overview and explains why ... It discusses resistance INI and their impact on reservoirs and possible eradication of HIV.
The article, in English, is here:
Integrase Strand Transfer record Resistance against Inhibitors and Relevance to HIV Persistence
Worth for dolutegravir, but not other INI (Isentress ® RAL or Stribild ® EVG). I will put a French translation soon ...
With Hypo-Dolu on newcomer, we have to move ... Hypo-Dolu he makes ICCARRE obsolete? In any case, he puts the spotlight on ICCARRE ... Those who, like me, have followed a method ICCARRIENNE, will know that they are good candidates for HYPO-DOLU
So my Field Guide remains valid ...
For a given patient, if ICCARRE 4/7 with TRIUMEQ ® does not work, then there is no chance that HYPO-DOLU walking
So ICCARRE remains in the race!
Tomorrow, Sunday, sleep and weekly intake, I did not need breakfast ...
Saturday, July 25, 2015
My doctor sucks!
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This paper was originally published here, in French. We are providing the google translation for your convenience
My doctor sucks!
My doctor sucks!Hypo-Dolu it's great ... And with ICCARRE, tested, validated 1/7 in reserve, Plan B is nickel! Hypo-Dolu thank you and thank you to Alain Lafeuillade
4 eminent clinicians in four different hospitals (Leibowitch, Katlama, Raffi and Lafeuillade, among others ...) explain to their patients that the treatment result has no reason to be the same as the initial treatment.
One 'sorts' not patients ... especially not in Toulon (Hypodolu) where they are not millions. At Toulon, Dr. Lafeuillade done with those volunteers ...
Patients who understand that the treatment of attack is one thing, and maintenance treatment another, are not privileged members of a caste or association ...
By chance, they fell to a doctor who, he understood. By chance ... or cronyism ... We keep it between themselves ...
I did not understand right away ... I put the time ... I'm not 'handpicked', and I do not have a cutter.
By against my doctor is zero. Not 100% no ... Sometimes he has good intuitions. But OK...
- TASP: treatment makes no contaminant, the virus stops where the treatment is effective: that he did not understand
- PreP: prophylactic treatment protects the virus stops where he is face to ARVs: that he did not understand
- Drug interactions, many of which are unknown, unsuspected, not considered: that he did not understand
- ICCARRE the cycle by reducing short remission =: that he did not understand. Or rather, he understood the interest ... But Môssieur can not do ... and deprives patients
- Hypo-Dolu ... Do not even think ...
Môssieur HIV Specialist is ... "It's interesting, but I do not know how" that's no good!
ICCARRE can be learned ... The Chinese, I do not say. But ICCARRE is simple!
I read (here ...) I cogitated, I tilted ... There is nothing magical. I read the 4 clinical studies, 4 studies and consistent walk. I got it. Tilt!
And I made the cut and I brought them closer CV: I'm not completely stupid: I'm in much better shape and the virus is still and always undetectable.
I understood and explained how to close the CV. It can be Learnt. I even made a handy little guide
Iccarre HIV cure HIV AIDS viral load test protocol relief program
http://i62.tinypic.com/2hofaty.jpg Under ICCARRE 1/7, Sunday is the weekly dose ... Cool ... Patient banal, trite profile banal combo, and ... almost-healed ...
Under HYPO-DOLU, being confirmed, it is similar. And Tivicay stamp, it is small, small. A relief ...
Good Weekend and good fuck
Saturday, July 18, 2015
hypo-dolu: an attractive once-weekly
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This paper was originally published here, in French. We provide the google translation for your convenience. Proper translation will come soon
hypo-dolu: an attractive once-weekly
Hypo-Dolu: 1/7 truly a very attractive
In ICCARRE 1/7, Dr. Jacques Leibowitch offers a complete lock reverse transcriptase. Beginning in 2015, Dr. Alain Lafeuillade offers maintenance treatment, single dose, weekly, lock integrase.
Alain Lafeuillade offers the following diagram: triple therapy based Tivicay ™ (eg Triumeq ™ or Tivicay ™ + Kivexa ™ or Tivicay ™ + Truvada ™) monitoring Tivicay ™ mono-therapy, then gradual reduction to 1 decision weekly. It seems that the official test to be considered as a first step in Toulon. It also appears that there have been some patients in this process.
The key idea is that dolutegravir (DTG) has little mutation sites that confer resistance, and that, if selected, these mutants have a viability ( 'fitness') so small that it is as if they were gone.
For Hypo-Dolu test, you can inform you here:
Press Release of 20/01/2015 (English)
HYPO-DOLU Lafeuillade HIV HIV treatment dolutegravir Tivicay Hypodolu once-weekly
Personally, I have enough validated my ICCARRE 1/7, and I admit that the proposal of Alain Lafeuillade easier to generalize, easier to swallow, 'and even more economical (at least in France. ..). So I decided to do HYPODOLU way ... This is ongoing, and I am very happy!
Obviously this method will change the perception of therapies weekly catch ... It's going to open the field ... A bit emulation will do good.
Here is the French translation of the press release Hypo-Dolu
January 20, 2015 (MMD Newswire) - Dr. Alain Lafeuillade, MD, PhD, said: The new inhibitor of HIV integrase dolutegravir is a very potent drug not only able to maintain HIV RNA <20 copies / ml in patients naive to treatment or switch patients in monotherapy, but also to maintain control of viral load with 50 mg three times a week, and sometimes twice a week.
Alain Lafeuillade, a clinical researcher for 20 years on HIV, observed that dolutegravir alone is very effective in patients without resistance to integrase. "The viral load remained undetectable in my patients, and proviral HIV DNA into the cells remained stable with only 50 mg 2-3 times a week with an average follow-up of 6 months, adds Dr. Lafeuillade. Therefore he proposed a protocol called "Hypo-Dolu" in HIV patients to determine, in the absence of resistance to integrase inhibitors, the minimum weekly dose of dolutegravir necessary. patients on two reverse transcriptase inhibitors, more dolutegravir 50 mg / day would be spent in dolutegravir mono-therapy for 3 months and then, if the viral load remained <50 copies / mL, will be passed to dolutegravir 50 mg every 2 days, and if the plasma viremia is still contained 50 mg twice a week, then once a week.
"There is hardly any risk of resistance selection, Doctor Lafeuillade added that the single mutation Selectee rarely dolutegravir by the codon 263 of the integrase gene significantly affects the viability of HIV, and that's why dolutegravir healing is tested in trials. Unfortunately, ViiV Healthcare n 'was not interested in the process, preferring to sell its drug at the highest dose, as tested in clinical trials, even if it was too high.
Dr Lafeuillade launch this test as a trial in his institution; he stressed that "in a difficult economic situation, it may be helpful to save medication if a single anti-retroviral triple therapy compared to -By-can do the job at lower doses, and it will also help to save the long-term side effects ".
Contact: Alain Lafeuillade
Head of the Department of Infectious Diseases
General Hospital, 54 rue Henri Sainte-Claire Deville
83100 Toulon, France
Ph: +33 (4) 94 14 50 84
Email: alain.lafeuillade ... then put the at sign, then ... ch-toulon.fr
Complete information is gathered here:
tinyurl.com/CHE-HYPO-DOLU
Several features of dolutegravir and its pharmaceutical form Tivicay ™ justify this approach: we will discuss on this blog. See: Monotherapy Tivicay ® (DTG)
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Sunday, July 12, 2015
Once weekly on prime time TV
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This paper was originally published here, in French. We provide the google translation for your convenience. Proper translation will come soon
Once weekly on prime time TV
1/7 submitted to 20 hours of TF1
Fast Forward >> In 2014, there was this story on TF1:
Iccarre HIV cure HIV AIDS AIDS relief organization Leibowitch Efavirenz
http://i59.tinypic.com/2qd1q8o.jpg When I read the first accounts (Alexandre Bergamini), with Leibowitch in Garches (ICCARRE), I thought the guys were either fantasists whether they had found something unique, that was out of my reach .
The method is explained right, left, is a bit scattered. By bringing together the snippets we can reconstruct the strategy, and the problem is solved. Except that conveys a lot of imprecise or inaccurate information that put the patient faces a risk of failure, and by the same strategy.
The 1/7 is maintained in a fog, mist fed ... Outside our Church 'no salvation: ICCARRE hospital will or will not: hogwash!
Just know the recipe and method ...
In light of recent publications relief in 5/7 or 1/7 are no longer hypothetical but fantasies a reality available to all.
I propose a practical guide for the beginner ICCARRIEN. We found it to:
Now that Leibowitch published, it is no longer needed to do in the politically correct. Besides ... Political correctness it intoxicates me ...
For my part, I take long to realize that this is great! But I finally understand ...
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Saturday, July 4, 2015
4 different proposals for relief
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This paper was originally published here, in French. We provide the google translation for your convenience. Proper translation will come soon. Some practical aspects may differ where you live.
4 different proposals for relief
Sunday, June 28, 2015
You are cured!
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This paper was originally published here, in French. We are providing the google translation for your convenience
You are cured! ICCARRE: Sir, you ARE Healed!
Sir, you ARE Healed!
Oh ... The title surprises ...
YET That is Fauci, Dybul, Leibowitch and other doctors, very advanced, the early days of triple therapy DIT Ë Have Their patients. With the disappointment Whether on SAIT
I said, sir, you ARE Healed. ARRÊTONS the treatment
At the bottom of p. 4, here:
www.tinyurl.com/CHE-REPI
ou here: CR_Recherche.pdf
and when I left Washington to pay Announce Results of triple therapy, it already Had Recurrence
Indeed, the sauce commit.
As I edited, pour facilitate dissemination, the micro-story of TF1, he turned loop and yes ... Turned in a loop, it's hard to Aunt Imagineur, We Are important pre-conditioning and traumatized by The Who fOREGOING.
However ... at 1/7, I'd say What can Leibo
Charles Edward, you ARE Almost Healed. ARRÊTONS gradually the treatment, and maintain weekly prophylaxis June. And when I went to Washington, and elsewhere, pour continuer my life, he had not Always Had Recurrence
So I OJEU 2015 ... and my i-Phone:
Yes, Jacques, I'm Almost Healed. So thank you Doctor ... Yes ... ICCARRE e Hypo-June Dolu gives response (partial) and YES ... on May cure HIV (and AIDS).
Healing almost certainly cure But anyway! ...
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