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This was originally published here, in French (link).
We provide this translation for your convenience. Practical aspects may differ where you live.



Help yourself: ARVs will help you

By Charles-Edouard!

The blog is assailed by SPAM, so: on a recent article, the messages are published immediately. On an old article, they are moderated...

Intermittency is unstoppable

When you're at 4/7, it's normal for 3/7 to tickle you. Each time, you are there and it works. And as it works, you are there; so why not go further? It's Darwinian and recursive: at each increment you, and your virus, are in a new environment. There is, strictly speaking, no intention. Some people stop, at the judgement, the pre-judgement shall we say, at X/7. But this is only temporary and it is only a matter of time before they resume their journey, each time more astonished by their extraordinary success: they believe it to be exceptional: it is not! Find me even one failure with Triumeq® in 2/7 or Eviplera® in 3/7!

The intention, or the goal, shall we say, is most often the fear of side effects. Once at 1/7, we can say, for sure, objective achieved! However, there is nothing objective about this: reducing an overdose by a factor of 15-25 (e.g. DTG) by a factor of 7 is not an objective success.

Toxicity is not my initial motivation

My entry into intermittence had nothing to do with toxicity, which, like many, I had not identified as such, and which had already done its work of undermining, with consequences and after-effects that would be discovered and that the simple change to 6/7 would reveal. I am familiar with this state of mind of the patient who does not see the insidious toxicity, denies it, I have shared it...

My personal interest does not come from there, so it is not confined to that. One school of thought envisages a reduction, or even disappearance, of the reservoir. We see from time to time a manipulation exploring latency reversal cocktails or the role of DTG. Latency inversion was my hobby. I did it. In France, I must be the only one! Because, if there is a clique of peroers, there has never been the slightest manipulation. They are reasoners in rocking chairs.

Ananworanich, close-up CVs and FASEB-1

I don't give the same credit to the latency reversal anymore, but I did do what Ananworanich did(first-in-class clinician), with one notable difference: where she has about 30 volunteers, 15 in each arm, I only have one on hand.

We try the cocktail, in double blind, and then we stop the treatment to see if there is a difference in time to rebound. For the moment, NADA... The time to rebound is identical in both arms (intervention and control): 2-3 weeks. The difficulty is not there... We have no clinical support for our legitimate explorations (American veterans do, so it is legitimate and ethical).

That's when I discovered that you can do CV without a prescription! It costs, but, it's possible. Except that... Here's what's not possible: interrupting the treatment and going to the lab to have a CV done on Monday and Wednesday, every week, until it comes back. At that time, the lab's FRAU had warned me: CVs outside of the prescription = OK, but cevetic relentlessness = NEIN. And at the time, the labs that offered this service were not numerous. Today, one could establish a wandering strategy and proceed exactly like Ananworanich...

Except that, here too, the Ananworanich method is not the best: you have to let the virus rise again, then you have to delete it again, which can take a long time and subjects you to the risk of seeing your doctor-secretary change your combo at the same time. Today, with DTG, retreatment is simple and without the threat of resistance. Today I will not hesitate, in fact I did not hesitate to resuppress with DTG as we have seen.

There I discovered FASEB-1, and the possibility to explore the Eclipse, gradually, by small steps. It's much longer, but the pharmaceutical savings(less toxicity) is already a good thing! Even if you fail to go into remission (you wouldn't be alone), you'd have as many boxes of medication left in the cupboard, and that's not bad. Maybe we'll come back to this one day...

My goal is remission!

I've put a little water in my wine and I'll be satisfied with a remission with small feetAt 1/30, I'll stop, it's not a big deal. At 1/30, I'll stop, I promise.

The current philosophy in this matter is anti-scientific: if you stop, the virus will always return and it's not true, we know that now: the Eclipse is and it is 2-3 weeks. In addition, there is a significant proportion of patients in whom replication does not resume until after a month, or even not at all. The alternative, orthogonal, is to say that if you take 7/7, you are sure to remain suppressed, which is also inaccurate: there are exceptions (we may come back to this).

Between these 2 orthogonal propositions, in exact opposition to each other and equally false, there is an unexplored field of possibilities: what happens when you go through a slow withdrawal? That nobody has done, except me: we make X/Y (X can be 1, 2 or 3, we will come back to that) and we extend Y: 7, 10, 12, 14,... 21...

The more we advance, the more we have tools (molecules, CV, tank measurement...) and concordant proofs on the Eclipse. But surprisingly, clinicians are not interested in this: when I talk about it, it's a flop, which proves that Silicianism is deeply rooted in the minds of people who are not known for their sagacity. The world without Peytavin, without Rouzioux and without Siliciano is nevertheless a world full of potentialities, accessible to everyone.

I'm going to 1/12!

My 1/10, in extra-Leibowitchian formula, this time, has been validated. The NFC-3 suits me very well (Charles-Edouard's New Formula!), so we're moving forward, carefully, as usual, and we'll come to complete, without batting an eyelid, new molecules, when the time comes. We are completely free from the goodwill of the medical-pharmaceutical underworldof all those pretentious people who never did anything. Free, finally free... And soon (semi-) cured!

overmedication is an opportunity if you know how to use it!