162

This was originally published here, in French (link).
We provide this translation for your convenience. Practical aspects may differ where you live.



4/7 in Italy! It's coming, it's coming...

By Charles-Edouard!

Very pertinent question, asked here:
What could be more natural than to think about it! When you see success rates of almost 100% in 4/7 for others, and a prolonged efficiency for yourself, you would like to think that limiting yourself to 5/7 would have been a missed opportunity. As it is iterative and Darwinian, the next increment is 3/7, it is obvious. This is not validated by a large clinical trial... So what??? it has not been invalidated either. If you don't even look for it, you can't find it!

The experimental method is described in FASEB-1: make sure of the good susceptibility of HIS virus (something that must have been done before initiating 4/7, so normally it's good), make sure of the efficacy at 4/7, don't try it under Isentress, Genvoya, Kaletra (but who still takes that?) monitor at the beginning by CV 1 month, 2 months, 4 months, 6 months (at the beginning only), and that's all! BIOLOGICAL follow-up necessary. The medical follow-up? Well... For the comfort of the mind? Maybe ? And still ... In any case, the medical follow-up in 3/7, did exist (100% success rate, subtracting the risk combos), and, in practice, it disappeared with Leibowitch...

What does the ANRS tell you? It could not be clearer: ' Get on with it'...

A new publication in 4/7

This publication comes from Italy. We had distributed our biblio to various clinicians. Including them... Did it help? I don't know. We can see that French works are abundantly cited (ICCARE, Leibowitch, Calin, ANRS-4D, Quatuor). Normal, there are not many others (Breather, in 5/7, at most...). The results are the same: 100% success, a few dropouts... It's like usual... Nothing new... And the nothing new is reassuring!

The very interesting discussion is in the body of the text. That's why I made a translation in french, in extenso. You have to read it. There is a vibrant tribute to ICCARRE, despite a small inaccuracy: Leibowitch et al. published in 2010 (FASEB-1 and 2015 FASEB-2), BREATHER was published in 2016, so Leibowitch is earlier, not the other way around...

The dosages... They are instructive!

They made 4 dosages per patient... It is instructive, because as in ANRS 4-D, there are cheaters, and it shows! There seems to be 1 or 2 who take more, but mostly a dozen, or a third, who take less. And it works just as well! It shows us the way: 4/7 is good to start... It's a start... And, after a while, you have to grow up

The threshold dose is a joke!

The threshold dose is determined by the failures when introducing the molecule in a new therapeutic scheme. Never in the long term, never... I challenge you to find a threshold dose at T plus 1 year that is equal to that seen in the short term. The good example is Nevirapine, with its dose-dependent failures at less than 6 months(thanks to poor tolerability in some), but no failure beyond 8 months. No failures: no threshold.

The authors discuss here the doses observed after 3 days of interruption (but perhaps more, the patients were just doing their own thing), and we are successful even at values well below the IC90. Note that the 'official' therapeutic dose is 3 times IC90 for Rilpivirine, while it is 15 times IC90 for the more effective Dolutegravir. Look for the mistake...

The Eclipse exists: we see it, so what does the threshold dose mean? Moreover, in the long term, we don't know how to determine it. In the stable phase, it's just a flan!

Can do better...

I like this kind of publication: it is an obvious progress in the percolation of ICCARRE at the international level. This publication is in addition to the others. This poses 2 problems:

- as long as one perceives that the Eclipse is only a few days long, for everyone(vision of the 2000s), it is quite logical to consider the results of others for a reflection on oneself. Now that we have Eclipses that are both longer and more dispersed, these tests on others, on non-identical viruses, no longer make any sense!

- The tests accumulate ad nauseam. Medical Darwinism obliges, it is only a question of time that we pass to 3/7... And what a waste of time! Obviously, if 4/7 is as 'good' as 7/7, it is no less 'bad'.

The 'enemy' of yesteryear was 7/7(will there still be people to practice it in a few years?). It has fallen. The new 'enemy' is the 4/7: it will necessarily fall one day...

In the news

- Satoshi Omura, Japanese Nobel Prize winner, presents I*T as a treatment against C*D: no doubt, a Nobel Prize is no match for 'fax checkers' without the slightest scientific background. It should be noted thatin vitro I*T is as effective on Omega as on the others...

- Before/After critical analysis of the pasteurian 'predictions', it's here, and it's scouring! (it's good too...)

- Very well documented article by Helene Bannoun: The origin of the Covid-19 virus

- Very interesting Evaluation of the methodological methodological practices implemented in Pfizer trials, by Christine COTTON

- Genetic Forcing, Self-Disseminating Vaccines, Chimeric Viruses... The sorcerers' apprentices of the genome by our excellent Bruno Canard, Étienne Decroly Jacques Van Helden (it's not free, but if you ask nicely...)

Pieces of Anthology

- The virus has not mutated,' says Professor Karine Lacombe on RTL (at 4 min 50 sec): To be enjoyed in moderation!

- Typhus, a little history on Science.org:

The French genius

Today is Saint Darwin's day! It was Lamarck who discovered Evolution. Darwin, the Evolution under pressure from Selection. This is still relevant, even if many advances have been made since then. Our French genius is Montagnier, who died on February 8.
If he had not set up the Pasteurian Laboratory on Oncoviruses, there would not have been the very lucrative patent, there would probably not have been Barré Sinoussi or Schermann at the head of this world competition. There would have been a genius, but not French...

We don't care about the rest, the squabbles, the greatness and the smallness. Read again Darwin, Descartes or Newton, it's not all rosy either; they also said some bullshit with no equal; history will sort it out.

The fact remains that for us, Montagnier was the beacon of a whole generation! In fact, I am interested in 2 concepts that he exposed:

- DNA does not integrate randomly anywhere (so depending on where it is integrated, it will be more or less active)

- silencing(passive reservoir) is a reasonable therapeutic goal(as for tuberculosis)

We will come back to this, it is inevitable, since it is our salvation...

Feel free to comment, like, share and use

Turn off the TV and don't be fooled by Pharisee venality

161

This was originally published here, in French (link).
We provide this translation for your convenience. Practical aspects may differ where you live.



Leibowitch on television

In an ancient post JCM declares (whom I thank, by the way):

The video 'Leibowitch chez Drucker (Vivement Dimanche)' has disappeared from YouTube (like almost everything that remains of Leibowitch as a testimony Video). I am working on archiving copies. I have the video, but I don't know where I found it. There is an audio track (which is more than enough), which you can listen to from the Valas website, here. I keep a copy, so let me know if the link disappears.

Michel Drucker:
We are going to welcome a great researcher who teaches at the Raymond-Poincaré hospital in Garches, an AIDS specialist... He was one of the pioneers of the discovery of the virus, I ask you to welcome Doctor Jacques Leibowitch...
You wanted him to be there because the way to treat yourself has changed...

Josiane Balasko: I have a friend who simply told me that Jacques was doing a test protocol on a hundred patients:
Instead of taking a lot of medication every day, people with HIV are taking much less, making their lives easier and more comfortable.

Michel Drucker: You invented triple therapy in the mid-1990s, and for the past 10 years you have been leading a project called Icare. Intermittent, short-cycle antiretrovirals remain effective, which means that you are in the process of demonstrating that it is possible to lighten the treatment while maintaining its effectiveness...

J. Leibowitch: It is possible to go a certain number of days without medication without the virus returning, i.e. after an effective attack treatment, conditions are such in the patient's body that the virus has difficulty in rebounding, a viral eclipse aka viral latency time that allows us to space out the antiretroviral bombardments.

Michel Drucker: So far, triple therapy is a lot of pills 7 days a week...

J. Leibowitch: The established rule, which I have a hard time getting the invention to work against, is that it's 7 days a week, otherwise you're going to hell.

Michel Drucker: Now it's between 4 times and 1 time a week...

J. Leibowitch: Some treatments can be stopped for up to 6 days a week without the virus having had time to rebound.

Josiane Balasko: What needs to be done to make this a widespread thing?

J. Leibowitch: The rule has to be changed. It's a question of psychology, of physiology, that's a lot less chemical medication...

Michel Drucker: However, we should not think that we can do this in a wild way...

J. Leibowitch: Self-prescribing is forbidden, it has to be driven by a doctor, and until now, doctors don't do it because the rule has not been changed, that's why I'm happy to be here to present the Iccarre project and the good news, which is the reduction from 40% to 85% of the drugs for those who have to take them for life.

Josiane Balasko: I will read an excerpt from a letter from one of his patients: I am 49 years old, I am HIV positive, today I testify to be heard. There are a few hundred of us patients who take triple therapy between 1 and 3 times a week instead of the 7 days a week recommended by the medical profession: for my part, I am at 3 days a week and everything is fine.
In addition, it is time to say that HIV-positive people on treatment do not infect their partners, i.e. they can have unprotected sex without transmitting the virus.
AIDS DOES NOT PASS THROUGH YOU BECAUSE I AM TREATED ...

Michel Drucker: This means that with these simplified procedures, HIV-positive patients under care are no longer transmitting the virus... Do you have trouble convincing your colleagues?

J. Leibowitch: Yes, because it was established the hard way, over the last 15 years where the marks were taken under difficult conditions - it was more the virus that was winning; so a rule was set up defensively, and to change it, the HIV-positive people have to demand it.
The rights of the HIV positive patient to be properly treated, the right to the right dosage, it will not just come to you, you have to ask for it, and I had a lot of trouble to get to you, and I thank the host and this patient.

Michel Drucker: So, it is a question of adjusting the antiviral doses to the strict minimum necessary and sufficient...

J. Leibowitch: Yes, this is the deontological medical rule, it is to adjust the treatments to what is necessary.

Josiane Balasko: You think that consuming less medication will piss off the laboratories?

J. Leibowitch: Let's not attack the laboratories, for the moment, it is the barons of the pulpit who manage the situation and they have a lot of trouble accepting that this pacifying and liberating revolution comes from them.
The good news is that we will be able to reduce from 40 to 85% when we change the rule, the bad news is that I am the only one doing it, it would be nice if others did it.

Michel Drucker: That's why you're here today. Thank you, Doctor. Goodbye, thank you.