Search This Blog

Saturday, November 28, 2015

individual testimonies


This paper was originally published here, in French. We provide the google translation for your convenience. Proper translation will come soon. Some practical aspects may differ where you live.

individual testimonies

personal experiences



Posted in the face of Charles-Edouard:

... I have a friend who starts following the experiences that are read on the forums, and in the end he is grilled with a molecule resistant to the virus ...
This is why it should not be limited to read reviews, personal stories on the internet! ... The good and the bad ... Why ?

Bad experiences:
They are rare, which is normal: the failure rate in tests is low. (5% when following a random selection protocol, and 0% if it is known navigate)
In addition, the one who tried would not lead off, he finds himself rather con; and do not brag. Too bad they do not testify, themselves, directly.
The man who saw the man who saw the man who saw the bear ... that's interesting but it does not count!

Good experiences:
iccarre friends richard cross cuts garches hiv
There are many, but the advantage is that one that makes relief feels better, including in his head ... the motivation to testify diminishes! One sentence, testimony, sums up:
Obsessed with HIV and its host of side effects are just a bad memory for me. Today HIV is not present in my life.

Leibo among patients, some gathered their testimonies in a book published, of great aesthetic quality; others have gone on TV: what more?
Clinical trials:

They are led by 'investigators' ... responsible for ensuring that we do not tell everything and anything. You have to read the tests, read the eligibility requirements, and reserves written by the investigators: they are certified testimonies.

Is it easy to read and understand?

NO. First have to find them, sometimes you have to pay for access, and is in English (technical). I still made the effort to collect and translate ALL ALL.

The latest is: www.tinyurl.com/CHE-FASEB2, and here on this blog.

Can we draw a line of conduct?
YES: there are now 4 trials published, documented and ongoing. 300 approx patients. it starts to make sales ... We will not wait until 1000 or 10000!

(The single IP therapy, validated by the report Morlat (ANRS) is 3 different options and it is only 1,200 patients ... it gives an order of magnitude)

But it is not easy to do ...

That is why I regret that no splint it and that, by, default, I formatted and available to all, proposal, argued, to discuss with her doctor.

Guideline is summed up in 3 words:

Effectiveness, progressiveness, close CV

- Carefully check the effectiveness of a strategy before moving to the next
- Getting there gradually
- Frequently check (to avoid a possible replication has bolted)

The individual testimonies are postcards. They make us perceive a territory.
Clinical trials are a mapping.

To resume a fashionable author: map has more value than the territory ...

The route is a path on the map; down the road postcards.
The reliable route is made possible by the card.
The practical guide 4/7, most popular document will soon be 1 year. I honed, but the important thing remains intact. If one day we have an RTU, RTU will be accompanied by a "Therapeutic Use Guide", inspired by the GTU proposed by the instigators of the RTU, in the opinion of the ministry.
It is based on the same card. It leads you to the same place. Wait a GTU (is it written?), It is expected that Marisol Touraine can read a map ...
Vast program ...

Explore a territory requires a conceptual corpus' and even the appearance of a new concept. Ch. Columbus westward from the East to find because believe that the earth is round, it's new.
Our newness, our paradigm shift is simple:
On a virus without mutation integrase (wild i.e. in terms integrase), the selectable mutations dolutegravir lead the virus reproductive impasse resistance never appears. 2 consequences:
- The efficiency is much higher than the usual glass beads
- Efficiency is independent of dose
Any dosage undetectable now is admissible. Understanding the nature of the dose dependence is made difficult because we are obsessed with the inefficiency of old molecules. This will require to change our vision, but facts are stubborn: the course is undetectable, and this can be achieved and maintained, even with low dosages.

I was comfortable with my ICCARRE 1/7 in quadruple, economical and effective. I ruled the world. From this height, the view opens, other peaks are nearby. I go back down in the dark valley polluted (7/7 ... yuck!), I'm going to climb another peak: it is not higher, but the way is without pitfalls ...

And I, still 1/7, on Monday ...

Good weekend and good fuck!

No comments:

Post a Comment

Note: Only a member of this blog may post a comment.