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Wednesday, December 1, 2021

183



This was originally published here, in French (link).
We provide this translation for your convenience. Practical aspects may differ where you live.


A giant step towards recovery and that's me!

By Charles-Edouard!

My tank has disappeared... or... did I make my tank disappear?


As long as you give a prize (INSERM) or a lot of $$, it would be nice to do it for a real real ization. And, to give to those who do. Not to the spectators! The spectators watch, amazed, admire and... Applaud!

Without further ado I reveal where I stand, and we discuss it afterwards. My tank is measured every year: 2015, 2016, ... 2018. Low but present, unequivocal. 2019 and 2020: three attempts where the lab said they were unable to do the measurement. 2021: the laboratory confirms the undetectability: it is without appeal: something happened!

And this something is huge: the disappearance of the tankit's gone under the radar! Now, if you find even one doctor capable of showing such a masterful Before-After, just let me know: I have never seen one: it is the GRAAL of the grail: no one has ever managed to do it, except by genetically modifying the individual and perhaps in the Biosantech trial (to be verified...). You know how to do this, you are part of the Kador, the STARS. And if you don't know how, well, you are not a STAR.

We are talking about DNA(measurement of the reservoir according to the ANRS method) and not RNA(whose undetectability is maintained by the ICCARRE+ method)

Under the radar! it is under the radar...


When the numbers are low, the validity of the results is questionable... Yes, yes, yes... And we'll do it again in 2022(if this stupidity of sanitary pass has ended, if not, we'll do it later, or elsewhere... ). I'm not worried or in a hurry... from 2015 to 2018, the lab was able to come out with results, but not in 2019 (twice...) we suspected something! Again in 2020... These are background noise problems: the signal is drowned in a small hubbub. So for 2021, I used a little trick (that I got from Ananworanwich) to try to get the signal back to the best I could dream of. Who knows... But at least the machine spit out something! It spit out ZéRo, and that's not nothing!

When does it go under the radar?


Good question... First, when it was above the radar, it was for real. How do we know? because several months before the last 'positive' reading, I had a (very) high RNA reading (at that level of CV, it's not a blip!). This virological failure, frankly, will have been recovered with brilliance, and above all, a few months after the incident, the reservoir was as usual, in conformity with the classical observation that a short period under active viremia does not affect the reservoir level.

So moving the tank, one way or the other, is no small feat! You make a controlled slip and it doesn't change your burden. The alla Pharisee argument that intermittency (or even failure) would make the tank go up (boo!...) is at odds with what we know. There is no need to worry unnecessarily...

I think that the passage under the radar dates from 2019, and that 2021 is only a confirmation. Besides, after 3 unsuccessful readings, we could have already ruled. And all these impossible or null measures, are in a series that starts in 2019 and interrupts an earlier series of remarkable consistency!

No more reservoir? What's the point? What to do next?


As long as you have a tank left, there are a lot of questions that don't arise! Nobody asks them... And when you don't have a tank anymore, everything comes up: you are in terra incognita! So, we'll see about that next time

Obligation of treatment / Judiciarization


When a virus comes from nowhere and appears 800 m from the only laboratory in the world working on these living viruses, we say that a pangolin has been killed by a bat. When a variant appears without any known recent emergence (despite 2 million genotypes!) we immediately find the source: an S+ patient with uncontrolled HIV... Oh well... The use of some mutagenic molecule? No ? Really? No? Well... If you say so. Of course, there were some who immediately decried the situation and wished it would end: hear, hear !

In the news


- Raoult said he reviewed a forthcoming article on a very large prophylaxis study at HCQ... Hi... Hi... He knows the result... Do you? Not yet... He seems quite confident about the future, don't you think?

- In the meantime, a large prophylaxis study with VMI confirms, not surprisingly, that it has a role to play!

- Merck announces that it has stopped its Islatravir study in 1/7, under a pretext as futile as it is unverifiable. Let's keep an eye on Merck's next announcements on Islatravir. I bet that they did not hang up their apron and that the others finally gave in in the negotiations... Merck's initial objective was always injectable. The oral form in 1/7 was only for as long as there was no injectable solution... And if the injectable that we feel is coming does not work, there will always be time to come back to 1/7, but in IRT, this time, as it would have been reasonable to do from the start... We'll see... The saga continues, and we will come back to it.

- bad luck: Pasteur (Lille) interrupts its clinical trial... For lack of patients! In the middle of the e-ieme wave! You have to do it!!! it's here. By dint of being soaped the board, it wears out!(Even Pasteur... Apart from laying down algorithmic elucubrations that leave one quite perplexed...)

- Pr S. Gayet is an infectiologist who seems to deal with nosocomial diseases in hospitals (of which Covid is a part...). Behind his phlegm and his Alsatian accent, he says exactly the same thing as Raoult. It is less brilliant, less striking, but it is kif and it is here.

- A stellar article by Norman Fenton, who notes a wave of deaths, NOT Covid, among NON-vaccinated people, coinciding with the (NON)vaccination campaign, whereas this campaign is, for them, a NON-event! The (non covid) deaths of the freshly vaccinated (side effect: death...) have been attributed... to the cohort of the ... NON-vaccinated. So, of course, when you correct the bias, it looks bad. It's a bit hard to read and it's here.

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I'm walking against the current, because I don't know how to walk against my heart...

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